The latest version of EpimiRBase is available for searching and for download in .csv format. The latest version includes data from 19 new publications. EpimiRBase now contains 2,189 entries from 89 publications including 1,246 unique microRNA from three species: human (222), mouse (871) and rat (1,096).
Author Archives: Brett Becker
New version of EpimiRBase reseased (January 2019)
The latest version of EpimiRBase is available for searching and for download in .csv, .xml and .json formats. The latest version includes data from 33 new publications. EpimiRBase now contains 2,152 microRNA-epilepsy associations (1,244 up and 907 down regulated) from 74 publications including 998 unique microRNA from three species: human (202), mouse (866) and rat (1,083).
New version of EpimiRBase released
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The latest version of EpimiRBase is available for searching and for download in .csv, .xml and .json formats. The latest version includes data from 7 new publications. EpimiRBase now contains 2,068 microRNA-epilepsy associations from 41 publications including 1,207 unique microRNA (1,198 up and 870 down regulated)
from three species: human (161), mouse (854) and rat (1,053).
EpimiRBase Published in Bioinformatics
EpimirBase has been published in Bioinformatics. Currently the paper is accessible through advance access. The final issue version will contain the volume, issue and page number details. The DOI of course, will not change. Please see below for a free-access link to the full text PDF.
Please cite as:
EpimiRBase: a comprehensive database of microRNA-epilepsy associations
Catherine Mooney; Brett A Becker; Rana Raoof; David C Henshall
Bioinformatics 2016;
doi: 10.1093/bioinformatics/btw008
Free-access link to full text PDF:
http://bioinformatics.oxfordjournals.org/cgi/reprint/btw008?ijkey=3rap30purtCBQT1&keytype=ref
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New version of EpimiRBase available for download
The latest version of EpimiRBase is available for download in .csv, .xml and .json formats. The latest version includes 2,055 microRNA-epilepsy associations from 34 publications including 973 unique microRNA (1,191 up and 864 down regulated)
from three species: human (161), mouse (849) and rat (1,045).
New publication added
EpimiRBase has been updated to include the work of a new publication contributing valuable information on mmu-miR-22-3p. Some of the coauthors of the paper are based at the Royal College of Surgeons in Ireland, the home of EpimiRBase. The paper was featured on thejournal.ie today.
In the article, Prof David Henshall (RCSI and EpimiRBase) said: “Epilepsy affects more than 37,000 people in Ireland and our study has shown promising results for the development of new treatments.We are looking forward to the next phase of the research which will potentially lead to a new type of drug that can tackle the underlying causes of epilepsy, reducing seizures and ultimately improving quality of life for people with the condition.”
The paper was published in Scientific Reports and is available here.
2 new publications, 390 new entries, 283 new microRNAs
EpimiRBase has been updated to include the work of two new publications resulting in 390 new entries and 283 new microRNAs. The new publications are:
EpimiRBase now contains 1,357 microRNAs across 2,148 entries from 31 publications.
EpimiRBase 1.0 released
Version 1.0 of EpimiRBase was released today. Epilepsy is one of the most common neurological disorders, affecting approximately 65 million people worldwide. MicroRNAs are short non-coding RNAs which function to fine-tune protein levels in all cells. They have been identified in the blood after injury to the brain and may serve as biomarkers of epilepsy.
EpimiRBase is a database of microRNAs associated with epilepsy extracted from published research. Version 1.0 has details from 30 publications on 1,796 MicroRNAs. Each microRNA has its own entry which features details shown below in addition to expression details, a link to the miRBase entry and a link to the original publication. Numbers in brackets are the number of entries in EpimiRBase for each microRNA.
- microRNA (1,796)
- regulation
- up (991)
- down (805)
- regulation
- type of study
- expression analysis (41)
- functional (10)
- profiling-biofluid (19)
- profiling-brain (1,726)
- species
- human (156)
- mouse (689)
- rat (951)
It is hoped that the community finds EpimiRBase helpful. We will be releasing future versions as we gather more information. If you would like to make your findings available in EpimiRBase, please contact us. Feel free to leave comments as well.